The cytoskeleton and motor proteins of human schistosomes and their roles in surface maintenance and host-parasite interactions

Article Abstract:

The organization of the cytoskeleton and associated motor proteins of schistosomes, with particular reference to the organization of the syncytial tegument, a unique cellular adaptation of these and other neodermatan flatworms are described. The biology of some components, particular those contributing to host-parasite interactions as well as chemotherapy and immunotherapy are discussed.

Cytoskeleton, Schistosoma

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Turning it up a notch: Cross-talk between TGFbeta and Notch signaling

Article Abstract:

Signaling through both the transforming growth factor TGFbeta superfamily of growth factors and Notch play crucial roles during embryonic pattern formation and cell fate determination. This study uncovers a direct link between the Notch and TGFbeta pathways and suggests a critical role for Notch in some of the biological responses to TGFbeta family signaling.

United States, Genetic aspects, Proteins, Drosophila

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