There is an upper limit of chromosome size for normal development of an organism
Article Abstract:
The relevance of chromosome size to the development of an organism was examined by microscopic analysis. The results confirmed that the longest chromosome arm should not be more than half of the average length of the spindle axis at telophase for an organism to develop normally. Beyond such length, the fertility and viability of the carrier individual become severely impaired because of the increasingly incomplete separation of the longest chromatids during mitosis which eventually results to loss of DNA.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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Bacteriophage DNA packaging: RNA gears in a DNA transport machine
Article Abstract:
Direct studies of virion structures, assemblies and genomic sequences have revealed more information about the nature of dsDNA bacteriophages and their genomic DNA on the inside of the virus particle. The development of in vitro packaging systems have significantly contributed to phage biologists' understanding of DNA packaging. A number of experiments have also shed light about the functions of pRNA in DNA packaging.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
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