Twenty-five years ago in Genetics: identical triplets

Article Abstract:

The genetics community has been embroiled in a debate regarding the role of deleterious mutations and heterzygosis in evolution. The classical view, espoused by H.J. Muller, regarded any increase in mutation rate as direct cause of a proportional increase in mutation load. However, the balance hypothesis, formulated by Dobzansky, argued that heterozygosity per se is the primary consideration rather than the genic content of the individual. In 1967, simultaneous publications of three papers confirmed the importance of hetrozygosis, although the problem of genetic variability and the genomic rate of deleterious mutations remain unsolved.

Analysis, Mutation (Biology), Mutation, Genetics, Heterozygosis, Heterozygote, Genetic load

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Birth defects, Jimson weeds and bell curves

Article Abstract:

Albert Francis Blakeslee, who was a leading geneticist in the early decades of the 20th century, was born on Nov. 9, 1874. Although he loved teaching, Blakeslee spent most of his time studying plant and animal species, particularly Jimson weed, Datura stramonium. He wrote 221 articles on wide-ranging topics dealing with fungi and Datura. Blakeslee received the Bowdoin Prize at Harvard for his discovery of heterothallism. His memory is perpetuated by the species Phycomyces blakesleeanus and the genus Blakeslea trispora. Blakeslee died on Nov. 16, 1954.

Biography, Genetic aspects, Birth defects, Jimson weed, Jimsonweed, Blakeslee, Albert Francis

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Sixty years ago: the 1932 International Congress of Genetics

Article Abstract:

The Sixth International Congress of Genetics held in Aug 1932 at Ithaca, NY, was attended by 562 people from 35 countries. Various exhibits on living organisms and visual materials on topics covering premolecular genetics were featured. The year 1932 approaches the end of classical genetics' peak and a number of noteworthy papers were discussed during the congress. More than 200 papers were presented in addition to the various plenary sessions. The president of the 1932 congress was T.H. Morgan.

International Congress of Genetics

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