Multipotent hematopoietic cells susceptible to alternative double-strand break repair pathways that promote genome rearrangements
Article Abstract:
A study to investigate the multipotent hematopoietic cells that are highly susceptible to alternative double-strand break repair pathways, promoting the genome rearrangements. Results show that these progenitor cells lead to the formation of chromosomal arrangements, promoting the several oncogenic events following DNA damage.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
To proliferate or to die: Role of Id3 in cell cycle progression and survival of neural crest progenitors
Article Abstract:
The helix-loop-helix transcriptional regulator Id3 has a novel role in cell cycle progression and survival of neural crest progenitors in Xenopus. Data suggests that Id3 functions by a novel mechanism, independent of cell fate determination, to mediate the decision of neuronal crest precursors to proliferate or die.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle. The generation of proper constitutive G-tails on yeast telomeras is dependent on the MRX complex
- Abstracts: Class III HD-Zip gene regulation, the golden fleece of ARGONAUTE activity?. part 2 'Mir'acles in hox gene regulation
- Abstracts: Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors. part 2 A long view of fashions in cancer research
- Abstracts: Molecular mechanisms for organizing the neuronal cytoskeleton. From genes to human diseases in cortical development
- Abstracts: A conserved blueprint for the eye? The evolution of arthropod segmentation mechanisms. Coming to our senses