An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets
Article Abstract:
A study presents an algorithm designed to extract motifs from large data sets of naturally occurring phosphorylation sites, a method that relies on the intrinsic alignment of phospho-residues and the extraction of motifs through iterative comparison to a dynamic statistical background. Results demonstrate the identification of dozens of novel and unknown phosphorylation motifs from newly published serine, threonine, and tyrosine phosphorylation studies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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RNA synthetic biology
Article Abstract:
Researchers have produced a novel, synthetic RNA components that are capable of regulating gene expression in vivo largely in bacteria and yeast, which have set stage for scalable and programmable cellular behavior. The immediate challenges, future directions and applications of engineered RNA-based systems are discussed.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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From words to literature in structural proteomics
Article Abstract:
The integrated strategies and tactics that can be used for characterizing molecular complexes and for describing their interactions in a cellular context are presented. A comprehensive description of the multitude of interactions between molecular entities is given.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2003
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