Changes in pig serum lipids, nutrient digestibility and sterol excretion during cecal infusion of propionate
Article Abstract:
Water-soluble fiber diet supplements have been found to lower serum lipids. Colonic fiber fermentation produces short chain fatty acids such as acetate, propionate and butyrate. Propionate inhibits cholesterol synthesis in vitro and may contribute to hypolipidemia. The effect of propionate infusions to the cecum on serum lipids, sterol excretion and nutrient digestibility was studied. The infusions did not lower serum lipid levels but caused a 15% increase in total serum cholesterol and LDL cholesterol. The changes in the other two parameters were not detectable. Propionate absorption appears to have no hypolipidemic effects.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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Dietary soluble fiber and cholesterol affect serum cholesterol concentration, hepatic portal venous short-chain fatty acid concentrations and fecal sterol excretion in rats
Article Abstract:
The effect of cellulose and soluble fibers such as pectin, psyllium and oat bran on serum cholesterol, hepatic lipid and hepatic venous short-chain fatty acid levels and fecal sterol excretion was investigated in rats. Cholesterol-fed rats had markedly lower total lipid and cholesterol levels in the liver if they were also fed soluble fiber in their diet. Various results for each kind of soluble fiber are described. The study suggests that soluble fibers in the diet may have a lower total serum cholesterol by increasing the fecal neutral sterol excretion.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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Soluble dietary fiber and cholesterol influence in vivo hepatic and intestinal cholesterol biosynthesis in rats
Article Abstract:
A study was done on the effects of soluble dietary fiber and cholesterol to hepatic and intestinal cholesterol biosynthesis in rats. Results show that diets supplemented with cholesterol increased the relative liver weight and correspondingly increased liver cholesterol in rats fed with cellulose and oat bran but not in those given pectin and psyllium. Cholesterol-supplemented diets produced higher liver cholesterol but not liver total lipid concentration with oat bran feeding as compared to cellulose-feeding.
Publication Name: The Journal of Nutrition
Subject: Food/cooking/nutrition
ISSN: 0022-3166
Year: 1992
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