Early dietary influence on later immunocompetence

Article Abstract:

The immune response takes shape in the maternal-fetal interaction and during breast-feeding. Maternal malnutrition and infection cause growth retardation in utero which often leads to an impaired immune response of the child. Breast-feeding further fortifies the immune system and prevents infections and inflammations. Vitamin A deficiency in both mother and child, a global health problem, produces low immune competence and serious complications. Immunological tolerance, the suppression of a specific immune reaction, may take place in response to the early introduction of certain foods.

Maternal-fetal exchange, Pregnancy, Malnutrition, Vitamin A deficiency, Malnutrition in pregnancy

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Meeting summary

Article Abstract:

A variety of prenatal and postnatal nutritional influences may affect fat metabolism, susceptibility to chronic disease, the onset of puberty, eventual fertility, and cognitive functioning later in life. Size in childhood is also genetically determined by maternal weight, height and pregnancy weight gain. Taller adults are less susceptible to heart disease, have a greater work capacity, and a better reproductive ability. Nutritional deficiencies impair the immune functioning profoundly. Further research and global health care policies for pregnant teenagers are urgently needed.

Child development, Prenatal influences, Disease susceptibility

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Early determinants of immunocompetence

Article Abstract:

Immunocompetence may be affected by T-cell and antibody developments during fetal and neonatal life, by placental feeding, and by breast-feeding during infancy. Oral tolerance, introduced early in life, plays an important role in immunocompetence, but the actual mechanisms involved in developing oral tolerance require further study. Breast-feeding appears to be crucial in preventing many types of infections and possibly even autoimmune diseases.

Research, Prevention, Autoimmune diseases, Nutrition, Immune system, Immunocompetent cells, Immunocompetence

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