A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees

Article Abstract:

A new T-cell hepatitis C virus (HCV) genetic vaccine for protecting chimpanzees from acute hepatitis induced by challenge with heterologous virus is discussed. Massive expansion of peripheral and intrahepatic HCV-specific CD8+ T lymphocytes that cross-reacted with vaccine and virus epitopes caused the suppression of acute viremia in vaccinated chimpanzees.

Care and treatment, Complications and side effects, Diseases, Control, Dosage and administration, Chimpanzees, Viral vaccines, Hepatitis C virus

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The process development challenge for a new vaccine

Article Abstract:

Regulatory, technical and manufacturing hurdles in translating a vaccine candidate to clinic are the major challenges of vaccines development. Process development is central to successful commercialization and also is a technological foundation that underlies the manufacture of new vaccines.

Production management, Manufacturing processes, Product Development, Market Research & Product Development, Evaluation, Production processes, Time to market

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Battle over eye medicine gives drugmaker a dose of reality

Article Abstract:

The impact of the decision of the biotechnology company, Genentech to withdraw its eye medicine, Avastin on the patients, as well as the doctors is discussed.

Commodity & service prices, Management dynamics, Goods & services distribution, Channels of Distribution, Management, Prices and rates, Distribution, Genentech Inc., Company business management, Monoclonal antibodies, Company distribution practices, Company pricing policy, DNA, Avastin (Medication)

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