Phenylpropanolamine and the risk of hemorrhagic stroke

Article Abstract:

Phenylpropanolamine may increase the risk of a hemorrhagic stroke in women, according to a study of 702 stroke patients and 1,376 health volunteers. Phenylpropanolamine is used in cough/cold medications and appetite suppressants.

Complications and side effects, Brain, Brain hemorrhage, Phenylpropanolamine, Adrenergic alpha-agonists

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A clinical trial of estrogen-replacement therapy after ischemic stroke

Article Abstract:

Estrogen replacement therapy does not reduce the risk of a second stroke in women who have had a first stroke, according to a study of 664 women. It also does not reduce mortality rates in women who have had a stroke.

Health aspects, Evaluation, Prevention, Hormone therapy, Estrogen, Estrogens

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A prognostic system for transient ischemia or minor stroke

Article Abstract:

Transient ischemic attacks are episodes in which a patient suffers partial weakness, blindness in one eye, and speech difficulty; they resolve in 24 hours or less. A minor stroke consists of any of these symptoms persisting more than 24 hours. Both episodes are known to increase a patient's risk of major stroke or death, but no useful system has yet been developed to classify these patients by their degree of risk for severe complications. A total of 142 patients who suffered either a transient ischemic attack or a minor stroke were evaluated for the presence of the various risks known to be associated with stroke. Their likelihood of suffering a major stroke or death within two years of the original transient ischemia or minor stroke was found to be related to several factors: being older than 65 years, having diabetes, and having severe hypertension. The results were compared and then pooled with those of a similar Canadian study. It was found that the presence of coronary heart disease and distinguishing between transient ischemia and minor stroke were also important factors in predicting the likelihood of severe complications. A scoring system was developed in which patients were assigned points for the presence of risk factors; those with the highest scores were more likely to proceed to major stroke or death. By combining the results of the two studies, a scoring system for transient ischemia and minor stroke was developed and is apparently quite successful at predicting which patients are at high risk for significant problems, and therefore most likely to benefit from early intervention. (Consumer Summary produced by Reliance Medical Information, Inc.)

Prognosis, Cerebral ischemia

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