Age distribution of Helicobactor pylori seroprevalence among young children in a United States/Mexico border community: evidence for transitory infection

Article Abstract:

Helicobactor pylori seroprevalence and age distribution in young children are discussed based on a study of 365 schoolchildren, 4-7 years old, in a low-income US/Mexico border community, where there was evidence for common transient infection without evidence that crowding is a strong predictor of infection and without any indication that birth or residence in Mexico was associated with seropositivity. In early childhood years spontaneous elimination of H. pylori may be common, and host characteristics or environmental exposures may affect susceptibility to persistent infection.

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The authors respond to Dr. Taylor

Article Abstract:

The dynamics of Helicobacter pylori infection in childhood are discussed, emphasizing that many questions and few answers exist in this area of study. Focusing on a narrow age range may indeed make some larger trend more difficult to see, but misconceptions about a monotonic increase in H. pylori prevalence with age in all populations have come from failure to acknowledge departures from the trend at younger ages in some populations, such as the disadvantaged studied group on the US-Mexico border.

Nutrition, Socially handicapped, Disadvantaged persons

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Dynamics of Helicobacter pylori infection in childhood

Article Abstract:

The dynamics of Helicobacter pylori infection in childhood are discussed relative to a study of children aged 4-7 in a poor Mexican-American community where it was found that prevalence of infection went down with increasing age. Differences should be interpreted with caution for several reasons, among them that a cohort effect may be in place, but no demographic or socioeconomic differences were found to account for the age-related seroprevalence decrease.

Children, Developing countries, Child health

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