Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies
Article Abstract:
Elevated blood levels of fibrinogen, C-reactive protein and white blood cells may increase the risk of coronary heart disease (CHD). These compounds are all associated with inflammation. Researchers searched the medical literature for all long-term studies of these factors and their association with CHD. Eighteen studies showed that people with the highest levels of fibrinogen or C-reactive protein had about twice the risk of CHD as those with the lowest. High white blood cell counts also increased the risk. On the other hand, elevated blood levels of albumin seem to lower the risk.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Fasting Insulin and Apolipoprotein B Levels and Low-Density Lipoprotein Particle Size as Risk Factors for Ischemic Heart Disease, Part 1
Article Abstract:
Fasting insulin and low-density lipoprotein cholesterol (LDL-C) particle size and levels may indicate the risk of ischemic heart disease. Researchers measured insulin levels and blood lipids in 85 men with heart disease and 85 men without heart disease. Men with increased fasting insulin apolipoprotein B levels and small, dense particles of LDL-C in the blood had almost six times the risk of heart disease, compared to those with normal levels. Measurement of these heart disease risk factors may improve the predictive value of traditional blood lipid profiles for cardiac disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Association of apolipoprotein E genotypes with lipid levels and coronary risk
Article Abstract:
The assessment report that suggests approximately linear relationships of apolipoprotein E (apoE) genotypes with both low-density lipoprotein cholesterol (LDL-C) levels and coronary risk is presented.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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