Chondrolipoangioma: a cartilage-containing benign mesenchymoma of soft tissue

Article Abstract:

Mesenchyme is an embryonic tissue that gives rise to connective tissue, as well as to blood vessels and the lymphatic system. Mesenchymomas are tumors of mesenchymal tissue, and they may be either malignant or benign. By definition, a mesenchymoma contains at least two mesenchymal tissue components not ordinarily found together, in addition to the fibrous tissue that is present in all such tumors. Unfortunately, however, it is difficult to obtain information concerning mesenchymomas. This is not only due to the fact that these tumors are uncommon, but also to the fact that many mesenchymomas end up being classified according to the tissue type that seems to be predominant, and thus information about these mixed tumors is buried within the medical literature. Benign mesenchymomas may, in fact, be more common than most pathologists appreciate. The authors present four cases of benign chondrolipoangioma. In these tumors, cartilage is the major tissue component. The cases are important, however, since they might easily have been mistaken for cartilaginous cancers and the patients could have been subjected to unnecessary surgical mutilation. Although atypical cells were present in several specimens, the overall appearance of the cartilage was benign, indicating that a few atypical cells can not be used as the distinguishing characteristic of cancer. Both the cartilage and the blood vessels in the specimens were clearly abnormal, which distinguishes the chondrolipoangioma from other tumors, such as choristomas. The benign tumors exhibited a wide array of tissue elements, including cartilage with some ossification, and mature adipose tissue and blood vessel tissues. The tumors were located near bone, but were not attached to bone. A careful study of mesenchymomas should permit their distinction from the malignant chondromas and chondrosarcomas. (Consumer Summary produced by Reliance Medical Information, Inc.)

Case studies, Diagnosis, Mesenchymoma

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Bone and soft-tissue tumors: benign or malignant?

Article Abstract:

Bone scans, X-rays, ultrasound, magnetic resonance imaging, computed tomography, tissue sampling, and blood tests are techniques used to identify disease type and progress in soft tissue and bone tumors. Patient age and tumor location may also help distinguish tumor types. Early identification can be critical for long-term survival. Characteristics of various invasive and noninvasive soft tissue and bone tumors and tools to identify them are presented.

Care and treatment, Tumors, Bone tumors

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The effects of botulinum toxin on ocular tissue

Article Abstract:

Botulinum toxin can be used to help patients with blepharospasm, which causes uncontrollable squinting. The condition is highly uncomfortable and patients can be rendered functionally blind. The toxin operates by working on the neuromuscular junctions and stopping the release of acetylecholine from the nerve terminals. Other conditions which can benefit from the use of the toxin include dystonias, corneal protection, and management of strabismus.

Usage, Botulinum toxin, Botulinum toxins

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