Cyclic ADP-ribose production by the CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is requited for bacterial clearance 'in vivo'
Article Abstract:
Research presented concerns the role of glycoprotein CD38 in promoting the production of cyclic ADP-ribose (cADPR), which in turn helps regulate calcium in the body. Findings suggest that cADPR also regulates chemotaxis in neutrophils and is implicated in the inflammatory immune process.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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NO vascular control in Duchenne muscular dystrophy
Article Abstract:
Research presented concerns the pathogenesis of Duchenne muscular dystrophy, focusing on how a lessening of muscle membrane-associated neuronal nitric oxide synthase may contribute to muscle degeneration. Topics addressed include cellular control mechanisms and vascular impairment.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo
Article Abstract:
Research has been conducted on the endothelial progenitor cells. The ability of these cells to replace the arterial endothelial cells and to promote patency in v-engineered small-diameter blood vessels has been investigated and discussed.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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