Defending the epithelium
Article Abstract:
Two studies examine the microbe-fighting peptides that keep infection at bay in the urinary tract and the colon. In the urinary tract, such peptides are deployed with the lightning speed, and in the colon a short-chain fatty acid induces the peptides and fends off dysentery caused by Shigella species.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
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Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas
Article Abstract:
The angiogenesis inhibitor pigment epithelium-derived factor (PEDF) is identified as a key inhibitor of stromal vasculature and epithelial tissue growth in mouse prostate and pancreas. How PEDF regulates normal pancreas and prostate mass is shown.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease
Article Abstract:
A vision threatening pathological neovascularization is caused due to retinal ischemia. The leukocytes that prune the retinal vasculature during normal development and obliterate it in disease is shown.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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