Do non-insulin-dependent diabetes mellitus and cardiovascular disease share common antecedents?
Article Abstract:
There may be progressive links between early-life nutritional deficiencies, the insulin resistance syndrome, non-insulin dependent diabetes mellitus (NIDDM), and heart disease. Inadequate nutrition at or before birth may lead to abnormal cell development in the pancreas that, in turn, may lead to obesity and the insulin resistance syndrome. Long-term stress on the cells of the pancreas may eventually cause them to fail, causing NIDDM. Symptoms that are characteristic of the insulin resistance syndrome, including excessive blood levels of insulin, obesity, and high blood pressure, are also risk factors associated with the development of NIDDM. Most of these risk factors are also risk factors for heart disease. However, there has been no conclusive research that directly links diabetes or aggressive management of this condition and heart disease.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
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Gluten-sensitive enteropathy in patients with insulin-dependent diabetes mellitus
Article Abstract:
It may be advisable to test patients with insulin-dependent diabetes mellitus for celiac disease if the patients have altered bowel habits. Researchers tested 47 patients with insulin-dependent diabetes mellitus for evidence of celiac disease. Three of the 47 patients (6.4%) tested positive for celiac disease with an antibody test as well as with biopsy. Two of these three also had tests to evaluate bone mineral density. Both of these patients had bone mineral densities that were two times lower than normal. Only one of these three patients had diarrhea symptoms characteristic of celiac disease. One of the patients tested for bone mineral density also did not absorb the sugar D-xylose at normal levels. None of the patients had low red blood cell counts.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
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