Dysplastic vulvar nevi

Article Abstract:

Nevi are moles or small dark spots on the skin. They are usually benign but in some cases they are severely abnormal and can even become malignant. When nevi become active and begin to increase in size or become darker in color, they are called dysplastic nevi. These nevi have the potential for becoming malignant (melanoma), and therefore require attention. Nevi are most commonly found on the upper body, arms, legs, buttocks, groin, scalp and breasts. Dysplastic nevi are rarely found on the vulva (the area around the opening of the vagina). Dysplastic nevi are more likely to be found on the upper body: in a study of 59 women with vulvar nevi, only one had a dysplastic nevus, while in another study of 200 patients with nevi on their torsos, 14 had dysplastic nevi. Of pigmented vulvar lesions in 500 women following childbirth, 18 vulvar nevi were discovered and removed, of which three were dysplastic. The dysplastic nevi were larger than five millimeters in diameter and were brown or black in color. Only one of the patients was aware that she had a vulvar nevus before seeing the doctor. It is concluded that dysplastic vulvar nevi may be more common than it was previous thought. (Consumer Summary produced by Reliance Medical Information, Inc.)

Development and progression, Vulva

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Increased prevalence of dysplastic and malignant lip lesions in renal-transplant recipients

Article Abstract:

People who have received a kidney transplant may have a higher risk of developing precancerous skin damage on their lips. Researchers examined the lips of 160 men and women who had received a kidney transplant and 160 healthy volunteers (the control group). Any lip lesions found were biopsied and examined under a microscope for evidence of malignancy. Twenty-three of the transplant recipients (14%) had lip lesions, but only one person in the control group had lip lesions. All but one transplant recipient had lesions on the lower lip. In 13 male transplant recipients, the lip lesion was precancerous or malignant. All of these men had spent considerable time in the sun. In fact, 69% were in the highest sun exposure category. They were also more likely to be smokers. However, rates of smoking and excessive sun exposure were higher in the healthy volunteers, indicating that continual immunosuppression was the major risk factor in the development of lip lesions.

Health aspects, Organ transplant recipients, Immunosuppression, Lips, Lip

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Dysplastic nevi

Article Abstract:

The diagnosis and treatment of dysplastic nevi are reviewed. Nevus (plural, nevi) is the medical name for a mole on the skin. Most normal moles are round, a single color, and no bigger than a pencil eraser. Dysplastic nevi are larger, not round, and bigger. People with dysplastic nevi who have a family history of melanoma should have an annual skin examination by a doctor.

Care and treatment, Diagnosis

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