Relation of Gemfibrozil Treatment and Lipid Levels With Major Coronary Events: A Randomized Controlled Trial
Article Abstract:
The cholesterol-lowering drug gemfibrozil can lower the risk of heart attack in men with low blood levels of HDL cholesterol, according to a study of 2,531 men. HDL cholesterol is the 'good' cholesterol that can protect people against heart disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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Clinical utility of different lipid measures for prediction of coronary heart disease in men and women
Article Abstract:
The effect of lipids on coronary heart disease on both sexes was studied and results documented.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
Article Abstract:
Gemfibrozil may lower the risk of heart attack, stroke, and death in men with low levels of high-density lipoprotein (HDL) cholesterol without high total cholesterol levels. Researchers administered the cholesterol-lowering drug or a placebo to 2,531 men. After about five years, 17% of the drug-treated men and 22% of the placebo-treated men suffered a heart attack or died -- a 24% reduction in risk due to the drug therapy. Gemfibrozil increased HDL levels and decreased blood triglyceride levels, but did not change low-density lipoprotein (LDL) cholesterol levels.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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