Immunoendocrinology of preterm labor: the link between corticotropin-releasing hormones and inflammation
Article Abstract:
Corticotropin-releasing hormone (CRH) might be one of the factors linking stress and inflammation to premature birth. CRH was first discovered in the hypothalamus of the brain, but it is also produced by the uterus and placenta. Rising CRH levels often signal the beginning of labor. An infection in the uterus leads to the production of immune chemicals called cytokines, which can stimulate the production of CRH. CRH can also influence the production of cytokines. These mechanisms may be one way infection can cause premature birth.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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Reproductive placental corticotropin-releasing hormone and its clinical implications
Article Abstract:
Corticotropin-releasing hormone (CRH) plays several important roles in pregnancy. CRH was originally discovered in the hypothalamus of the brain, but is also produced by the ovaries, placenta and uterus. Most of the CRH produced by the reproductive system is inhibited by CRH-binding protein, which is produced by the liver. However, during the last few weeks of pregnancy, blood levels of the binding protein drop and levels of CRH rise. CRH stimulates the production of prostaglandins, which leads to labor.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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Fetal heart rate patterns in term labor vary with sex, gestational age, epidural analgesia, and fetal weight
Article Abstract:
Doctors who monitor the fetal heart rate need to take the baby's sex into account. Researchers analyzed the fetal heart rate in 1,884 fetuses during the last hour of labor. The female fetuses had faster heart rates than the male fetuses. Epidural anesthetics, fetal weight, and the duration of labor also affected fetal heart rate. Fetal heart rate is usually monitored to detect severe illness in the fetus.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
User Contributions:
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