Informed consent for genetic research on stored tissue samples
Article Abstract:
A panel of scientists, lawyers, consumers and ethicists has recommended that informed consent should precede any procedure that removes tissue samples from a person if those samples could be used in future research. This is especially important if the samples are linked to information that could be used to identify the person who contributed it. In the case of anonymous samples, informed consent may not be necessary but the use of the samples should be evaluated by an institutional review board (IRB). The person contributing the sample should decide whether they want to be contacted in the future and whether they want their identity linked to the sample. The panel also recommended that Congress pass legislation to ensure the confidentiality of the samples and to protect the person who contributed them from discrimination if research determines they have a genetic disorder.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
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Hereditary nonpolyposis colon cancer
Article Abstract:
Individuals with a family history of colorectal cancer who have the gene for hereditary nonpolyposis colon cancer (HNPCC) should have regular colonoscopies. HNPCC is a dominant gene that causes the development of colorectal cancer at a relatively early age. A panel of experts from the Cancer Genetics Studies Consortium reviewed the literature on HNPCC and came up with a set of recommendations. The panel recommends colonoscopies every 1-3 years for those with the HNPCC gene beginning at age 25. The panel does not recommend removing the colon to prevent colorectal cancer.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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Informed consent for population-based research involving genetics. (Health Law and Ethics)
Article Abstract:
A task force created by the Centers for Disease Control and Prevention describes the development of an informed consent form for genetic research. Genetic research can be morally problematic because it can uncover a genetic susceptibility to a disease for which there is no effective treatment.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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