Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis
Article Abstract:
There appears to be some evidence of a link between Chlamydia pneumoniae (C. pneumoniae) infection and advanced heart disease. Heart vessel samples from 12 patients undergoing heart transplants were tested for evidence of C. pneumoniae infection using various laboratory methods. One patient with plaque deposits in the blood vessels, or atherosclerosis, had evidence of C. pneumoniae using all these laboratory methods. Seven of 10 patients with atherosclerosis had evidence of C. pneumoniae using at least one laboratory method. None of the patients without atherosclerosis had evidence of C. pneumoniae.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
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Predictors of systemic embolism in patients with mitral stenosis: a prospective study
Article Abstract:
Patients with mitral valve stenosis and atrial fibrillation, atrial clots, or aortic regurgitation may be at higher risk for systemic embolism. The opening of the heart valve is restricted in mitral stenosis. Researchers studied 534 patients for several years to determine important risk factors for blood clots to travel from the heart to peripheral blood vessels. Older patients, those with the disordered heart rhythm of atrial fibrillation, and those with an incompetent aortic valve were at higher risk for embolization. The mitral valve commissurotomy procedure reduced the risk.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1998
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Can degenerative aortic valve stenosis be related to persistent Chlamydia pneumoniae infection?
Article Abstract:
Aortic valve degeneration in elderly people could be a result of persistent infection with the bacterium Chlamydia pneumoniae. The aortic valve is one of the heart valves. Researchers examined the aortic valves from 46 human cadavers and also tested tissue samples for the bacterium. No valve damage was found in 20- to 40-year-old cadavers, but valve damage was found in older cadavers. Eighty-three percent of the older damaged valves tested positive for the bacterium, as did 44% of younger valves with no damage.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1998
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