Keratinocyte growth factor in the promotion of human chorionic gonadotropin production in human choriocarcinoma cells
Article Abstract:
Keratinocyte growth factor plays a role in the development of the placenta. During pregnancy, the fetal membranes must penetrate the lining of the uterus and this growth factor contributes to this process by stimulating the production of human chorionic gonadotropin by fetal membranes.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
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Increased interleukin-6 levels in peritoneal fluid of infertile patients with active endometriosis
Article Abstract:
Interleukin-6 (IL-6) may play a major role in the development of endometriosis and subsequent infertility. Endometriosis is a disorder where menstrual tissue migrates out of the uterus to other organs. Researchers collected abdominal fluid from 39 women who underwent laparoscopic surgery for either removal of ovarian chocolate cysts or an infertility workup. Women with active endometriosis lesions had much higher levels of IL-6 and tumor necrosis factor-alpha (TNF-alpha) than women without endometriosis. IL-6 is an indicator of inflammation. Endometriosis lesions, stimulated by TNF-alpha, may produce IL-6.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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Menstrual cycle-specific inhibition of the proliferation of endometrial stromal cells by interleukin 6 and its soluble receptor
Article Abstract:
Interleukin-6 appears to have different effects on the endometrium. The endometrium is the inner lining of the uterus. Researchers analyzed the effect of the immune system chemical interleukin-6 on samples of endometrial tissue taken at different times during the menstrual cycle. Interleukin-6 had no effect on endometrial cells taken during the proliferative phase of the menstrual cycle but it did affect the cells taken during the secretory phase. This effect during the secretory phase was blocked by soluble interleukin-6 receptor, which blocks the action of interleukin-6.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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- Abstracts: Fetal membrane distention: determination of the intrauterine surface area and distention of the fetal membranes preterm and at term
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- Abstracts: Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd Collection revisited
- Abstracts: The relationship among inflammatory lesions of the umbilical cord (funisitis), umbilical cord plasma interleukin 6 concentration, amniotic fluid infection, and neonatal sepsis