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Nicotine Metabolism and Intake in Black and White Smokers

Article Abstract:

Racial differences in the metabolism of nicotine and its metabolite, cotinine, could explain racial differences in tobacco-related diseases. Researchers measured blood cotinine levels in 40 black and 39 white smokers to estimate nicotine uptake while smoking and how quickly cotinine is eliminated from the body. Nicotine intake per cigarette was 30% greater in blacks compared with whites and blacks eliminated cotinine much more slowly than whites. If black smokers are exposed to more nicotine and cotinine while smoking, this could explain their higher risk of tobacco-related diseases.

Author: Perez-Stable, Eliseo J.MD, Herrera, Brenda MS, Jacob III, Peyton, Benowitz, Neal L. MD

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

User Contributions:

Comment about this article or add new information about this topic:

Nicotine Metabolism and Intake in Black and White Smokers

Article Abstract:

Racial differences in the metabolism of nicotine and its metabolite, cotinine, could explain racial differences in tobacco-related diseases. Researchers measured blood cotinine levels in 40 black and 39 white smokers to estimate nicotine uptake while smoking and how quickly cotinine is eliminated from the body. Nicotine intake per cigarette was 30% greater in blacks compared with whites and blacks eliminated cotinine much more slowly than whites. If black smokers are exposed to more nicotine and cotinine while smoking, this could explain their higher risk of tobacco-related diseases.

Author: Perez-Stable, Eliseo J.MD, Herrera, Brenda MS, Jacob III, Peyton, Benowitz, Neal L. MD

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

User Contributions:

Comment about this article or add new information about this topic:

Nicotine Metabolism and Intake in Black and White Smokers

Article Abstract:

Racial differences in the metabolism of nicotine and its metabolite, cotinine, could explain racial differences in tobacco-related diseases. Researchers measured blood cotinine levels in 40 black and 39 white smokers to estimate nicotine uptake while smoking and how quickly cotinine is eliminated from the body. Nicotine intake per cigarette was 30% greater in blacks compared with whites and blacks eliminated cotinine much more slowly than whites. If black smokers are exposed to more nicotine and cotinine while smoking, this could explain their higher risk of tobacco-related diseases.

Author: Perez-Stable, Eliseo J.MD, Herrera, Brenda MS, Jacob III, Peyton, Benowitz, Neal L. MD

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

User Contributions:

Comment about this article or add new information about this topic:

Subjects list: Measurement, Physiological aspects, Smokers, Smoking, Cotinine, Blacks

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