Perinatal mortality and congenital malformations in infants born to women with insulin-dependent diabetes mellitus - United States, Canada, and Europe, 1940-1988
Article Abstract:
Women with insulin-dependent diabetes are at increased risk for delivery of an infant with congenital malformations, stillbirths, and obstetric complications. Congenital malformations are the most common cause of perinatal mortality of infants born to these women. The incidence of congenital malformations and perinatal mortality were determined by examining hospital data from the United States, Canada, and Europe. There was an increase in the percentage of congenital malformations associated with perinatal mortality among infants born to women with insulin-dependent diabetes from 1960 to 1988 in the countries studied. Perinatal mortality continually decreased from 1940 to 1980 and can be attributed to improved prenatal care. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1990
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A prospective trial of risk factors for sulfonylurea-induced hypoglycemia in type 2 diabetes mellitus
Article Abstract:
Elderly patients with type 2, or adult-onset, diabetes may be able to take sulfonylurea drugs without worrying about developing hypoglycemia. This drop in blood sugar has been a concern among elderly diabetics, who are often not given these drugs for that reason. Researchers measured blood glucose levels during 23-hour fasting periods in 52 elderly type 2 diabetics while they took glyburide, glipizide or a placebo. None developed hypoglycemia during the study. Blood epinephrine levels increased during the fasting periods in those who took the drugs. This could protect the brain against hypoglycemia.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Prospects for Research in Diabetes Mellitus
Article Abstract:
New methods of delivering insulin to the body can control blood sugar levels and prevent the development of diabetes complications. Islet cell transplants can replace dysfunctional islet cells. The identification of predisposing genes can lead to preventive treatments.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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