Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: A pilot study
Article Abstract:
A study was conducted to determine if the variation in genes of pharmacological interest were associated with the pharmacokinetic and pharmacodynanic profile of indinavir (IDV), zidovudine (ZDV), and lamivudine. Results revealed that the novel relationships were identified among genetic variants in drug transporters and indinavir, lamivudine-triphosphate, and zidovudine-triphosphate concentrations.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Risk factors for in utero and intrapartum transmission of HIV
Article Abstract:
A study is done to identify predictors of in utero and intrapartum HIV-1 transmission in infants born in the women and infants transmission study between 1990 and 2000. The result showed that there has been an increase in the proportion of infections transmitted in utero, while there has been significant declines in perinatal HIV-1 infection over time.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life
Article Abstract:
The safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in 26 infants during the first six weeks of life is described. It is found that nelfinavir is well tolerated by the infants, with few adverse events attributed to the drug.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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