Seroepidemiology of cytomegalovirus in patients with advanced HIV disease: influence on disease expression and survival
Article Abstract:
Invasive cytomegalovirus (CMV) disease in HIV-infected people appears to occur in specific risk groups. Researchers followed 196 HIV-infected people who had a history of an AIDS-defining illness or a CD4 count less than 200 and had been tested for CMV. A total of 160 (82%) were CMV-positive. All of the black women were CMV-positive regardless of their risk group and 99% of the homosexual men were CMV-positive. CMV-positive rates were much lower in whites and Hispanics, heterosexuals and hemophiliacs. Eighty-six percent of the CMV-negative patients were non-black and heterosexual. One-fourth of the CMV-positive patients had invasive CMV disease, and 75% of these had CMV retinitis, which is an inflammation of the retina. Invasive CMV disease occurred most often in homosexual men and heterosexual men and women. Invasive CMV disease was much less common in intravenous drug addicts. CMV-positivity did not significantly affect survival or the time it took to develop another AIDS-defining illness.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Use of the dementia rating scale as a test for neuropsychological dysfunction in HIV-positive IV drug users
Article Abstract:
Neuropsychological testing instruments are valuable in assessing HIV-positive intravenous drug abusers (IVDA). The early diagnosis of neuropsychological disorders is essential for treatment planning. The Mattis Dementia Rating Scale was used to screen 21 IVDA patients. Results indicated differences in scoring among IVDAs which implied increasing dysfunction in HIV-positive than in HIV-negative patients. Thus, the Dementia Rating Scale is a valid testing instrument for assessing neuropsychological abnormalities in this population of drug abusers.
Publication Name: Journal of Substance Abuse Treatment
Subject: Health
ISSN: 0740-5472
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
The stability of neuropsychological test performance in a group of parenteral drug users
Article Abstract:
Neuropsychological tests and retests were adminstered to 16 parenteral drug users to test the stability of their performance in tests of general intellectual function, abstract reasoning, verbal memory, language, atention, visuospatial abiliy, set switching, speeded performance and manipulaitve dexterity. The Selective Reminding Tests and Perdue Pegboard were the only tests which showed instability.
Publication Name: Journal of Substance Abuse Treatment
Subject: Health
ISSN: 0740-5472
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Systemic lupus erythematosus patient guide: influence on knowledge of the disease. part 2 Abnormalities in the regulation of variable region genes that encode for antibodies to DNA may be a central factor in the pathogenesis of systemic lupus erythematosus
- Abstracts: A controlled trial of tacrine in Alzheimer's disease. Cholinesterase Inhibition for Alzheimer Disease; A Meta-analysis of the Tacrine Trials
- Abstracts: Gently does it. Treating obesity in people with learning disabilities. Sexual awareness
- Abstracts: The effectiveness of treatment for substance abuse: reasons for optimism. part 2 Decision tree for the management of substance-abusing psychiatric patients
- Abstracts: Psychoanalysis of a man with active alcoholism. A development model of addictions, and its relationship to the twelve step program of Alcoholics Anonymous