The effect of toll-like receptors and toll-like receptor genetics in human disease

Article Abstract:

The impact and the significance of the toll-like receptors (TLRs) and toll-like receptor genetics in the immune responses of humans against different diseases are discussed. The TLR genetics is shown to be extremely important in providing information on the gene-environment interactions in the health and diseases of the patients.

Gene expression, Genetic polymorphisms, Immune response

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Array-based DNA diagnostics: let the revolution begin

Article Abstract:

The article discusses benefits of using array-based copy number analysis (ABCNA) and genotyping in the field of DNA diagnostics. It is shown that the array-based DNA sequencing can be easily used for the diagnostic analyses of rare mutations and is also capable of full individual genome sequencing.

Usage, Nucleotide sequence, Base sequence, Mutation (Biology), Mutation, DNA microarrays, Single nucleotide polymorphisms

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Expanded newborn screening: implications for genomic medicine

Article Abstract:

The benefits of employing tandem mass spectrometry (MS/MS) along with the process of newborn screening (NBS) for genomic testing are discussed. The approach is found to be extremely useful for the development of predictive, preventive and personalized genomic medicine.

Analytical Laboratory Instrument Manufacturing, Analytical instruments, Ion Mass Spectroscopy, Health aspects, Genetic aspects, Technology application, Infants, Genetic screening, Genetic testing, Mass spectrometry

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