Urea kinetics: comparison of oral and intravenous dose regimens
Article Abstract:
A study onurea kinetics was conducted on five adults with normal hemoglobin genotype (HbAA) and four who were homozygous for sickle cell disease (HbSS). It was shown that significant hydrolysis of urea occurred before absorption causing questionable results for urea kinetics. In a study done on isotope given intravenously, HbSS subjects salvaged more urea-N than HbAA which indicate thatthere is a difference in urea kinetics between HbSS and HbAA and that oral presentation of isotope can be used to measure urea kinetics provided that exclusion is done for subjects who show upper intestinal hydrolysis.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1992
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Urinary 5-L-oxoproline (pyroglutamic acid) excretion is greater in infants in Jamaica than in infants in England
Article Abstract:
Jamaican infants aged six weeks excrete far higher levels of urinary 5-L-oxoproline than six-week-old English infants. Pre-term and full-term infants in England consistently exhibited different 5-L-oxoproline excretion levels, while pre-term and full-term infants in Jamaica excreted similar levels. Excretion levels of the Jamaican and English infants were the same at birth, but increased substantially in six-week-old Jamaican infants. The six-week-old Jamaican infants exhibited a marginal glycine status, possibly because of a dietary limitation of vitamin B-12 or folate.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1997
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Urea kinetics varies in Jamaican women and men in relation of adiposity, lean body mass and protein intake
Article Abstract:
The urea kinetics in obese and lean women and heavy and light men are studied. Results show that urea production and hydrolysis in obese women and heavy men are higher compared to lean women and light men. The rate of urea production and hydrolysis in obese women is due to increased fat mass while those in heavy men are due to protein intake. Obese women and heavy men also had higher rate of excretion of 5-L-oxoproline in urine.
Publication Name: European Journal of Clinical Nutrition
Subject: Health
ISSN: 0954-3007
Year: 1997
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