Ethical Considerations in Leaping from Bench to Bedside

Article Abstract:

Animal experimentation became more widely used as antivivisectionist opposition became more acceptable in developing interventions for human diseases. Scientists used less self-experimentation. Proposals for human gene therapy receives more public attention and a more public process of review. The Recombinant DNA Advisory Committee accepts preproposals involving severe combined immunodeficiency disease caused by adenosine deaminase deficiency and [Alpha} thalassemia has prompted considerable public interest.

United States, Political aspects, Animal experimentation, Animal rights movement

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Researchers Urged Not to Inject Virulent HIV Strain Into Chimps

Article Abstract:

Eleven researchers, conservationists, and primatologists have published a letter raising ethical and scientific objections to the injection of chimpanzees with a strain of HIV that can bring about an AIDS-like disease. Great apes are the only animals that have shown the ability to be infected by HIV-1. Details of the controversy are discussed.

Chimpanzees, Human-animal relationships, Chimpanzees as laboratory animals, Laboratory primates

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Staging ethical AIDs trials in Africa

Article Abstract:

The development and implementation of ethical guidelines lag behind the rapid growth of AIDs research in Africa. The massive numbers of HIV-infected individuals in Africa reduces research costs and time. But establishing clinical review boards and attaining informed consent have yet to become routine.

Editorial, Science and technology policy, Africa, Research ethics

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