Inner workings of a transcription factor partnership
Article Abstract:
Combinatorial control of transcription is based upon partnerships between two proteins that belong to different groupings. Such combinations add stability and specificity to protein-DNA interactions. Findings on the interaction between GABP (alpha) and its heterotypic partner GABP (beta) are reported.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
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Small nucleolar RNAs guide ribosomal RNA methylation
Article Abstract:
Recent research reveals that small RNA species (snoRNAs) in the nucleolus act as guides for rRNA methylation. Pre-RNA molecules are paired with specific snoRNAs, which together target sites fort methylation and identify the nucleotide to be modified.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
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