Postmenopausal hormone therapy and cognitive function in healthy older women

Article Abstract:

Postmenopausal hormone therapy and cognitive function in healthy older women have been studied based on data from the Nurses' Health Study, an ongoing prospective cohort study. Neither current nor long-term hormone users show better performance on an overall measure of cognition or on three test of verbal memory than never users. Current hormone users scored significantly better than never users on the test of verbal fluency, having a 30% decrease in risk of a low score on the verbal fluency test.

Demographic aspects, Drug therapy, Hormone therapy, Communication, Communications, Cognitive therapy

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Higher basal cortisol predicts verbal memory loss in postmenopausal women: Rancho Bernardo Study

Article Abstract:

Higher basal cortisol has been found to predict verbal memory loss in postmenopausal women. Interventions that block dysregulation of the cortisol axis may give new therapeutic options to prevent cognitive decline. Activation of the hypothalamic pituitary axis is a major component of the stress response and can cause impaired hippocampal structure/function and/or cognitive problems. The conclusions are based on findings on a subset of the subjects of the Rancho Bernardo Study in California and involved 749 postmenopausal women of mean age 72 years.

Abnormalities, Stress (Psychology), Menopause, Hydrocortisone, Neurology, Aged women, Elderly women, Geriatrics, Hippocampus (Brain)

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Dependence in activities of daily living and cognitive impairment strongly predicted mortality in older urban residents in Brazil: a 2-year follow-up

Article Abstract:

Research on urban Brazilian residents aged 65 and older suggests that cognitive status and degree of dependence in performing activities of daily living are successful predictors of mortality. Studies were based on 1,667 subjects from various socioeconomic backgrounds.

Brazil, Mortality, Patient outcomes, Risk factors, Activities of daily living, Cognition in old age, Old age cognition, Brazilians

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