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Global views of leukaemia

Article Abstract:

The newly developed high-density DNA microarrays are used for the characterization of cancer genome, including a type of leukaemia, which helps to identify the common abnormalities in genomic copy number that underline the disease. The author suggests that new strategies and plans for fixing the defects in cellular differentiation caused by recurrent loss-of-function mutations need to be devised to cure cancer.

Author: Golub, Todd R.

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007

Usage, Genetic aspects, Leukemia, DNA microarrays, Clinical report

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Drivers and passengers

Article Abstract:

Human Cancer Genome project was proposed by U.S. National Cancer Institute and National Genome Research Institute to find out mutations that contribute to manifestation of cancer by sequencing of genes in tumor samples.

Author: Haber, Daniel A., Settleman, Jeff

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007

United States, Gene mutations, Gene mutation, Nucleotide sequencing

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Subjects list: Research, Cancer, Cancer genetics

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