Comparison of selection methods at the same level of inbreeding

Article Abstract:

At a low level of inbreeding, genetic respones to selection are directly related to the accuracy of selection by using best linear unbiased prediction with informationon relatives, however, as levels of inbreeding are increased, wherein family information are more closely related, the use of blup becomes limited. An alternative was suggested in which blup may be compared with other selection methods, namely phenotypic and index, at the same level of inbreeding. The differences between methods were small if inbreeding was unrestricted but the values derived may not be optimal in all cases which may suggest revision and reevaluation of methodology used in the study.

Research, Usage, Inbreeding, Linear models (Statistics)

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Estimation of effects of single genes on quantitative traits

Article Abstract:

Analysis of the effects of single genes on quantitative traits by ordinary least squares can lead to erroneous results showing significant effects of the genes when no effect exists. The error can be due to mode of inheritance, selection intensity, heritability of the polygenic effects on the trait, magnitude of gene effect, data structure and gene frequency. It is argued that the use of an individual animal model can provide unbiased estimates of single-gene effects. The conditions under which this procedure is applicable are discussed.

Analysis, Gene expression

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Reduced animal model with differential genetic grouping for direct and maternal effects

Article Abstract:

Genetic evaluation of animals for breeding can be done using a reduced animal model. An algorithm was developed that allows computing breeding values of parents and nonparents by incorporating direct and maternal genetic groups. When dam information is missing, inclusion of breeding values of 'phantom dams' indicating direct and maternal effects avoid misspecifications in the computations of variance and covariance components.

Models, Genetic aspects, Animal genetics, Animal breeding

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