Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
Article Abstract:
The mechanism of ETV1 outlier expression in human prostate tumours and prostate cancer cell lines is explored. The identification of distinct classes of ETS gene rearrangement has demonstrated that dormant oncogenes can be activated in prostate cancer by juxtaposition to tissue-specific or ubiquitously active genomic loci.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
Methane oxidation by an extremely acidophilic bacterium of the phylum Verrucomicrobia
Article Abstract:
An extremely acidophilic methanotroph that exhibits taxonomically, ecologically and genetically diverse methanotrophy is described. Its phylogenetic placement in the phylum Verrucomicrobia and its extremely acidophilic phenotype are its distinct properties.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
Delineation of prognostic biomarkers in prostate cancer
Article Abstract:
It has been possible to identify many links between genes and prostate cancer. By directly comparing hybridizations of normal and neoplastic tissues, this work emphasized genes that molecularly distinguish benign tissue from malignant.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Salt sellers challenge US health agency using data-quality act. Dolly: A decade on
- Abstracts: Wildlife caught in crossfire of US immigration battle. Green activists enlist penguins to save the world. Merck opts for shake-up to clear drug pipeline
- Abstracts: Rab3A is essential for mossy fibre long-term potentiation in the hippocampus. Synaptic scaling mediated by glial TNF-alpha
- Abstracts: Visualization of transient encounter complexes in protein-protein association
- Abstracts: Enzyme target to latch on to. A century-old debate on protein aggregation and neurodegeneration enters the clinic