Retrotransposon reverse-transcriptase-mediated repair of chromosomal breaks
Article Abstract:
Researchers have discovered that retrotransposons and the reverse transcriptases (RTs) they encode may be beneficial to their hosts. Studies on over-expressed HO endonuclease in Saccharomyces cerevisiae revealed that retrotransposons and RTs are able to heal such chromosomal breaks. Previous studies have shown that RTs are essential components in the replication machinery of retroviruses such as HIV.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
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Base-excision repair of oxidatine DNA damage
Article Abstract:
The article examines the base-excision repair pathway of guanine oxidation products and explains the clinical, chemical and biological properties of these pathways.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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- Abstracts: The structural basis of specific base-excision repair by uracil-DNA glycosylase. Improving enzymes by using them in organic solvent
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