Gene silencing in worms and fungi
Article Abstract:
A similar protein is used by the nematode Caenorhabditis elegans and the fungus Neurospora crassa to control the process of gene silencing, even though these organisms have very different mechanisms of gene silencing. It appears that these organisms may share an ancestral mechanism that evolved to protect the genome against foreign DNA. This research supports the view that homology-dependent gene silencing phenomena evolved from an ancestral mechanism designed to protect the genome against transposons and viruses.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Enhancement of cellular memory by reducing stochastic transitions
Article Abstract:
The parameters that determine the stability of cellular memory are investigated using the yeast galactose-signalling network as a model system. The results provide a quantitative understanding of the stability and reversibility of cellular differentiation states.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Engineering stability in gene networks by autoregulation
Article Abstract:
Research involving designing and constructing simple gene circuits made up of a regulator and transcriptional repressor modules in Escherichia coli is presented. The gain of stability produced by negative feedback is demonstrated.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Local inhibition and long-range enhancement of Dpp signal transduction by Sog. Noise-induced enhancement of signal transduction across voltage-dependent ion channels
- Abstracts: Cooling and freshening of the subpolar North Atlantic Ocean since the 1960s. Old radiocarbon ages in the southwest Pacific Ocean during the last glacial period and deglaciation
- Abstracts: Radiocarbon evidence for extensive plate-boundary rupture about 300 years ago at the Cascadia subduction zone
- Abstracts: An epithelial serine protease activates the amiloride-sensitive sodium channel. An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel
- Abstracts: The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway