Keeping synapses up to speed
Article Abstract:
For the rigorous performance of the nervous system, the synapses must be active over a wide range of frequency stimulation. A steady link between the synaptic vesicles and the cytomatrix of nerve terminals, created by synapsin, controls the release of synaptic vesicles. The synapsin also helps in providing synapses the plasticity essential for the complicated activities in the nervous system. The synapsin II-knockouts have the damaged phenotype and the synapsin I-knockouts reveal the neurotransmitter release at the synapse.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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Ubiquitination-dependent mechanisms regulate synaptic growth and function
Article Abstract:
It has been established that ubiquitin-dependent mechanisms control synaptic development at the Drosophila neuromuscular junction. It appears that a balance between positive and negative regulators of ubiquitination controls the structure and function of the synapse.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Translating activity into plasticity
Article Abstract:
A description is presented of the effect of brain activity on the structure of individual nerves and nerve networks. The use of synaptic modifications by the brain to develop its nerve networks is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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