Mice and flies head to head
Article Abstract:
The orthodenticle (otd) and empty spiracles (ems) genes of the fly Drosophila strikingly resemble Otx and Emx, the homologous genes in mice. This resemblance, confirmed by Antonio Simeone and colleagues, suggests that the evolution of developmental gene expression in vertebrates and insects may have been more similar than previously thought. However, further comparative and experimental genetic research is necessary to prove that this is a case of evolutionary conservation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Patterning goes Sonic
Article Abstract:
The secreted Sonic hedgehog (Shh) protein is a bona fide morphogen that activates the transcription of various genes in a dose-dependent manner. Shh is among many vertebrate homologues of the Drosophila gene called hedgehog (hh), which plays an important role in patterning a developing fly's segments. Shh is similar to hh because expression is highly localized and is confined mostly to the notochord and floor plate during the early embryogenetic stages.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Small genome, big insights
Article Abstract:
Tetraodontiformes, are the two species which share a feature of great convenience for genomics: their cells possess less DNA than those of any other group of back-boned animals - about eight or nine times less than human cells. Together they have generated a genome sequence of impressive accuracy and cover-age, with 64% of the DNA sequence mapped to specific chromosomes.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: AIDS against the rest of the world. Save the beaches, not the buildings. Disease-of-the-month alive and well
- Abstracts: Ban on primate trade seen as threat to animals. European Environment Agency still in limbo
- Abstracts: p53, guardian of the genome. A death in the life of p53. Checkpoint policing by p53
- Abstracts: Court says US law applies to Antarctic waste cleanup. Choice to head NIST defines shift in US technology policy
- Abstracts: A degree of success for MRes courses. How to help universities meet obligation and opportunity. Slump in seed-corn: British enrolments in science courses are responding to market forces - and falling