Structural basis for the spectral difference in luciferase bioluminescence
Article Abstract:
The crystal structures of wild-type and red mutant (S286N) luciferases from the Japanese Genji-botaru in complex with high-energy intermediate analogue, 5-O-[N-dehydroluciferlyl)-sulfamoyl]adenosine (DLSA) are reported. Comparing these structures to those of the wild-type luciferase complexed with AMP plus oxyluciferin reveals a significant conformational change in the wild-type enzyme but not in the red mutant.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity
Article Abstract:
A mechanism for achieving methylation state selectivity involving the orientation of the structure of JMJD2A in complex with a set of histone H3K9 and H3K36 substrates and products of different Iysyl methylation states is presented.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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The structural basis for activation of plant immunity by bacterial effector protein AvrPto
Article Abstract:
The structural basis and the crystal structure for the activation of plant immunity by the bacterial effector protein, AvrPto is explained. The protein is found to trigger disease resistance and programmed cell death.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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