The future of cloning
Article Abstract:
It may be possible in the 21st century to link cloning techniques with other cell-biological procedures to move towards a form of tissue-replacement therapy that overcomes the difficulties of immune rejection. It is not yet practicable to link therapeutic cloning with the use of differentiation factors, but this approach offers potential for the future. The first stage would be to use nuclear transplantation to reprogramme the nucleus of a human adult cell, obtaining a blastocyst. After obtaining a certain number of cells, it would be necessary to differentiate them in the required direction.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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DNA microsatellite analysis of Dolly
Article Abstract:
Analysis of DNA from Dolly, the first animal cloned from an adult mammal, showed that she contained seven microsatellite alleles the same as those occurring in the cell population from which she was derived. It has recently been asserted that Dolly could have been derived from a stray fetal cell rather than from a mammary cell itself, but this is unlikely. A detailed analysis to determine the origin of Dolly is presented and it is concluded that she was derived from a mammary cell of the donor ewe.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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Cloned pigs produced by nuclear transfer from adult somatic cells
Article Abstract:
The successful production of cloned piglets from adult somatic cells using nuclear transfer, is reported.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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