Architecture of the Hin synaptic complex during recombination: The recombinase subunits translocate with the DNA strands
Article Abstract:
A site-directed protein crosslinking is used to elucidate the configuration of protein subunits and DNA within the Hin synaptic complex and to follow the movement of protein subunits during DNA strand exchange. The results indicated that the protein interface mediating synapsis is localized to a region within the catalytic domains thereby positioning the DNA strand on the outside of the Hin tetrameric complex.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
DisA, a busy bee that monitors chromosome integrity
Article Abstract:
A protein, DNA integrity scanning protein (DisA) is described, that is responsible for the surveillance of chromosome integrity during sporulation. This has enabled researchers to detect the localization of specific proteins even in small microbial organisms.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: A reanalysis of the indirect evidence for recombination in human mitochondrial DNA. Direct evidence of recombination in human mitochondrial DNA
- Abstracts: PCR detection of genes encoding nitrite reductase in denitrifying bacteria. Activity and composition of the denitrifying bacterial community respond differently to long-term fertilization
- Abstracts: MCM8 is a MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation
- Abstracts: Endocytosis conducts the cell signaling orchestra. Nobel celebrates the neurosciences: modulatory signaling in the brain
- Abstracts: Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation