Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q
Article Abstract:
Mapping of autosomal dominant orthostatic hypotensive disorder to chromosome 18q is discussed with information about three families and a genomewide scan in the two largest ones. General regulatory pathways in the range of blood pressures that exist may be better understood if the gene responsible for orthostatic hypotensive disorder in the families is identified.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
Article Abstract:
A genomewide screen of the families with late-onset Alzheimer's disease (AD) is a genetically isolated community from the southwestern area of The Netherlands is presented. This genomewide screen has displayed significant linkage to chromosome 3q23 markers and the analysis has confirmed linkage to chromosome 11q25.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
Association of polymorphisms in the angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community
Article Abstract:
A study to understand the association of polymorphisms in the angiotensin-converting enzyme gene with Alzheimer disease (AD) in an Israeli Arab community is presented. The results suggest that a variant in close proximity to rs4343 and rs4351 modulates susceptibility to AD in this community.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
- Abstracts: Integration of microbial ecology and statistics: a test to compare gene libraries. Status of microbial census
- Abstracts: New thermophilic and thermostable esterase with sequence similarity to the hormone-sensitive lipase family, cloned from a metagenomic library
- Abstracts: Sox2 is required for development of taste bud sensory cells. Rapid accumulation of mutations during seed-to-seed propagation of mismatch-repair-defective Arabidopsis
- Abstracts: Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Coactivator cross-talk specifies transcriptional output