Cosuppression comes to the animals
Article Abstract:
It has been possible to make some very interesting discoveries about cosuppression in animals since the early 1990s. Researchers have been able to demonstrate silencing of tandemly repeated gene copies in animals, and recent work has also clearly shown silencing of dispersed copies. Research into cosuppression in plants indicates that it is a generic phenomenon, being triggered by several different transgenes and by unusual duplications of endogenous genes. Repression linked with cosuppression seems to take place by different mechanisms in different cases.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response
Article Abstract:
The phosphorylation cascade induced by phosphorylation of the tomato Pto-interacting 1 (Pti1) protein kinase by Pto induces the hypersensitive response (HR). Pti1 expressed in tobacco plants increases HR in response to an avirulence gene. Pti1 is a serine/threonine kinase and acts downstream of Pto. It is unable to phosphorylate Pto or Fen, a related kinase. The HR confers gene-for-gene disease resistance to the plants.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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