The bacterial flagellum: from genetic network to complex architecture
Article Abstract:
The construction and subcellular morphogenesis of the bacterial flagellum involves several regulatory mechanisms that are also involved in preferential virulence factor transport from bacterial cells to their hosts and in phage assembly. The bacterial flagellum is arranged into three subassemblies, a propeller, a transmembrane motor and a universal joint. Introduction of the MS ring into the inner membrane signals the start of flagellar assembly. A checkpoint mechanism regulates the transcriptional response to the assembled structure.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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Bacterial chromosome segregation: is there a mitotic apparatus?
Article Abstract:
The complex mechanisms of bacterial chromosome segregation based on the replicon theory are characterized by chromosome-membrane attachment and membrane to cell wall synthesis. The process of bacterial chromosome segregation involves the initiation of bi-directional DNA replication followed by ParA/ParB-mediated bi-polar attachment and decatenation. The bacteria then undergoes septation and subsequent asymmetric cell division. Furthermore, the decantenation process is vital phase of chromosome alignment.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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Cell type-specific phosphorylation and proteolysis of a transcriptional regulator controls the G1-to-S transition in a bacterial cell cycle
Article Abstract:
Researchers have investigated the activation of the global transcriptional regulator CtrA by phosphorylation. It was possible to demonstrate that the progression of the Caulobacter cell cycle is determined by the phosphorylation of CtrA at mid S phase and by the proteolysis of CtrA at vital stages in the cell cycle. CtrA is present in the swarmer cells, is degraded during the swarmer-to-stalked cell transition and returns during mid S phase.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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