The osmotic stress response and virulence in pyelonephritis isolates of Escherichia coli: contributions of RposS, ProP, ProU and other systems
Article Abstract:
Pyelonephritis isolates of Escherichia coli have been studied with attention to the osmotic stress response and virulence and contributions of ProP, RposS, ProU and other systems. It appears the E. coli strains K-12 and CFT073 have an osmoregulaotry mechanism different from trehalose or betaine accumulation and not shared by E. coli HY734. It confers osmotolerance at the low salinity characteristic of human urine. Osmoregulatory betaine accumulation accelerates growth in high-osmolality media.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
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Osmoregulatory transporter ProP influences colonization of the urinary tract by Escherichia coli
Article Abstract:
Scientific tests are conducted to determine the direct and indirect relationship between osmoregulatory betaine accumulation, environmental osmolality and the capability of uropathogenic Escherichia coli to infect the urinary tract. A murine model for urinary tract infection was created using E. coli HU734. Results confirm the influence of osmoprotective betaine accumulation and transporter ProP in the growth of the bacteria.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
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Plasmid transfer in the animal intestine and other dynamic bacterial populations: the role of community structure and environment
Article Abstract:
Plasmid transfer in the animal intestine is discussed relative to other dynamic bacterial populations and the role of community structure/environment. Experiments have been carried out with the goal of clarifying whether plasmid transfer in the mouse gut shows kinetics expected of a mixed liquid-flow system. Transfer kinetics seen were very like those of a biofilm and not like those anticipated in a mixed, liquid culture.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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