A prospective, double-blind, randomized, controlled clinical trial of ampicillin-sulbactam for preterm premature rupture of membranes in women receiving antenatal corticosteroid therapy
Article Abstract:
Antibiotic therapy combined with steroid therapy may improve infant outcomes in pregnancies complicated by preterm premature rupture of membranes (PROM). Researchers treated 112 women from 23 to 35 weeks of pregnancy with preterm PROM with either three days of ampicillin-sulbactam followed by amoxicillin-clavulanate, three days of ampicillin followed by amoxicillin, or placebo. Women 32 weeks' gestation and under received corticosteroid therapy. Three infants died; all were in the placebo group. The ampicillin-sulbactam therapy was most effective at reducing infant death, infection, and maternal infection, and at increasing birth weight.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Fetal fibronectin: a new tool for the prediction of successful induction of labor
Article Abstract:
The presence of fetal fibronectin in vaginal fluids may prove a useful means of predicting successful induction of labor. Among 160 women undergoing labor induction, 15% of women with positive fibronectin tests had cesarean sections versus 27% with negative tests. Length of time from start of induction to delivery averaged 21 hours in the positive group versus 36 hours in the negative group. Fibronectin predicted success independently of the Bishop score, a physical evaluation of labor readiness. Among women with low scores, 22% with positive fibronectin tests had cesareans versus 35% with negative tests.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Fetal fibronectin detection as a predictor of preterm birth in actual clinical practice
Article Abstract:
Fetal fibronectin in cervical fluid samples in pregnant women is a fairly accurate sign of premature labor. This as the conclusion of a study of 151 pregnant women who had a fetal fibronectin test within seven days of delivery.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: In vitro studies of the interactions between platelets and amniotic membranes: a potential treatment for preterm premature rupture of the membranes
- Abstracts: Management of cervical cerclage and preterm premature rupture of the membranes: should the stitch be removed? The effects of L-arginine on the release of prolactin from decidual explants in vitro
- Abstracts: Reduction of postoperative pain: a double-blind, randomized clinical trial. The performance of bonded vs. pin-retained complex amalgam restorations: a five-year clinical evaluation
- Abstracts: Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming
- Abstracts: Outdoor air pollution, low birth weight, and prematurity. Impact of air pollution on reproductive health