Active tuberculosis in HIV-infected injecting drug users from a low-rate tuberculosis area
Article Abstract:
The incidence of active tuberculosis in HIV-infected drug addicts may be relatively low if the surrounding community has a low incidence of tuberculosis. Researchers identified 27 cases of active tuberculosis among 905 HIV-infected intravenous drug addicts treated at Saint Francis Hospital and Medical Center in inner city Hartford, CT. In 67%, Mycobacterium tuberculosis, the bacterium that causes tuberculosis, was isolated from tissues other than the respiratory system. Only six percent of those with a positive tuberculin test or history of successfully treated tuberculosis developed active tuberculosis. Between 1984 and 1992, the annual incidence of active tuberculosis in these drug addicts was less than one percent. Only one of the drug addicts who developed active tuberculosis had a history of active tuberculosis or a positive tuberculin test before the HIV diagnosis.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Quantification of HTLV-II proviral copies by competitive polymerase chain reaction in peripheral blood mononuclear cells of Italian injecting drug users, Central Africans, and Amerindians
Article Abstract:
Precise measurements of the amount of human T cell leukemia virus type I (HTLV-I) and type II (HTLV-II) may now be possible with the use of a new competitive polymerase chain reaction (PCR) test. Researchers used the test to measure the amount of HTLV-II in 11 Italian intravenous drug users infected with the virus and in 10 HTLV-II positive Amerindians and Central Africans from groups among whom HTLV-II is thought to be a native disease. The amount of virus in all 21 individuals varied greatly. HTLV-II positive patients who were also HIV type 1 positive had varying amounts of HTLV-II. The variations in amount of HTLV-II were determined not to be associated with native area, age, or sex. HTLV-II may have cloned itself in patients with large amounts of the virus.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Identification of IIa and IIb molecular subtypes of human T-cell lymphotropic virus type II among Italian injecting drug users
Article Abstract:
There appear to be two different subtypes of the human T-cell leukemia virus type II (HTLV-II) in Europe just as there are in North America. Researchers isolated HTLV-II from blood samples from Italian intravenous drug users and sequenced the gene that produces the gp21 envelope protein. This gene sequencing revealed two new isolates that were closely related to American isolates in the HTLV-IIa subtype. Previously, most European isolates belonged to the HTLV-IIb subtype.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Advances in detecting and responding to threats from bioterrorism and emerging infectious disease. 'New variant' Creutzfeldt-Jakob disease and bovine spongiform encephalopathy
- Abstracts: Risk factors for HIV infection in a national adult population: Evidence from the 2003 Kenya Demographic and Health Survey
- Abstracts: Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Rabbit antithymocyte globulin versus basiliximab in renal transplantation
- Abstracts: Testing for HIV infection at home. AIDS prevention - sexual ethics and responsibility. Potential use of home HIV testing
- Abstracts: Prevalence, incidence, and risks for HIV-1 infection in female sex workers in Miami, Florida. HIV prevalence and sexual behavior in a cohort of New York City gay men (aged 18-24)