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Getting to the heart of DiGeorge syndrome

Article Abstract:

Several genes may be involved in DiGeorge syndrome, which could complicate the development of gene therapy for this disorder. DiGeorge syndrome affects the heart, face, thymus gland and parathyroid glands. Many patients must have open heart surgery and also suffer from immunologic and endocrine disorders.

Author: Izumo, Seigo, Schinke, Martina

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999

Genetic aspects, Immunological deficiency syndromes, Immunologic deficiency syndromes

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Delivering genes to the heart -- right where it counts!

Article Abstract:

The author cites genetic animal experiments in which the gene transfer is done directly into the heart of the fetus. She believes this may ultimately be used with humans to prevent congenital heart defects.

Author: Nabel, Elizabeth

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999

Statistical Data Included, Research, Prevention, Fetus, Birth defects, Growth, Gene therapy, Fetal development

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