The effect of Leboyer delivery on blood viscosity and other hemorheologic parameters in term neonates
Article Abstract:
Delivery by the Leboyer method may increase blood viscosity in newborns, which could lead to impaired blood flow to vital organs. Various blood flow indicators were studied in 15 children delivered by the Leboyer method and in 15 children whose umbilical cords were clamped within 10 seconds of delivery. Children delivered by the Leboyer method had their cords clamped three minutes after delivery. Blood samples were collected from the newborns two hours, 24 hours and five days after birth. Residual blood in the placenta was 20 milliliters per kilogram less in the Leboyer-delivered infants indicating the transfer of an additional 20 ml/kg of blood to these infants. In the first two hours after birth, the hematocrit rose significantly in the Leboyer infants. The hematocrits taken at 24 hours indicated a range of 38% to 48% in the infants who had early cord clamping and 50% to 65% in the Leboyer group. Relative viscosity and hematocrit values rose within the first two hours in the Leboyer group but did not change over the first five days. No infants in this study developed any complications as a result of these changes.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1993
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Lack of effect of antenatal indomethacin on fetal cerebral blood flow
Article Abstract:
Treating pregnant women with indomethacin does not appear to increase the risk of brain hemorrhage in their prematurely born infants. Indomethacin is used to stop premature contractions, but some studies suggest that it may increase the risk of brain hemorrhage in prematurely born infants. Twenty-four women less than 30 weeks pregnant were randomly assigned to receive brief treatment with either indomethacin or magnesium sulfate to stop contractions. Doppler studies of blood flow within the brain did not reveal any adverse effects with indomethacin. Infants receiving indomethacin were no more likely to experience brain hemorrhage.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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Polymerase chain reaction determination of RhC, Rhc, and RhE blood types: an evaluation of accuracy and clinical utility
Article Abstract:
Polymerase chain reaction (PCR) analysis of Rh antigens in blood may be less accurate than standard blood tests but may cause fewer complications because it is less invasive. Researchers used PCR to test 655 DNA samples of which the Rh antigen status had already been determined using standard blood tests. The true positive detection rates for Rh C, c, and E by PCR was 98.3%, 98.1%, and 96.9%. The true negative rates were 91.5%, 94.7%, and 99.2%. PCR requires fewer invasively obtained samples, such as through amniocentesis, for analysis, so it may produce fewer complications.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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