Progesterone reduces lipopolysaccharide induced interleukin-6 secretion in fetoplacental chorionic arteries, fractionated cord blood, and maternal mononuclear cells
Article Abstract:
The effect of progesterone (P4) on lipopolysaccharide (LPS) induced interleukin-6 (IL-6) production in fetoplacental artery explants, fetal granulocytes, and fetal and maternal mononuclear cells are examined. Results reveal that P4 downregulates IL-6 production in both maternal and fetal mononuclear cells and chorionic arteries, with the most significant response to progesterone pretreatment seen in fetal cord blood mononuclear cells and maternal mononuclear cells.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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Pregnancy discovered after smallpox vaccination: Is vaccinia immune globulin appropriate?
Article Abstract:
The prophylactic treatment with vaccinia immune globulin for pregnancies that are exposed to smallpox vaccine in this vaccinia is proposed. The existing medical literature is reviewed to assess the risks of fetal vaccinia in these pregnancies and the controversy regarding the prophylactic use of vaccinia immune globulin.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
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17-hydroxyprogesterone caproate reverses induced vasoconstriction of the fetoplacental arteries by the thromboxane mimetic U46619
Article Abstract:
A study determines whether the progestational agent 17-hydroxyprogesterone caproate (17P) has a vasoactive effect on fetoplacental vasculature. Results demonstrate that 17P reverses induced vasoconstriction by the thromboxane sympathomimetic U46619 in fetoplacental arteries.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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