Reduction in triglyceride level with N-3 polyunsaturated fatty acids in HIV-infected patients taking potent antiretroviral therapy

Article Abstract:

Randomized double-blind study was conducted to assess the effect of N-3 polyunsaturated fatty acids (PUFAs) on hypertriglyceridemia of highly active antiretroviral therapy (HAART)-treated patients. Because of the high benefit/risk ratio of the product, N-3 PUFAs could be proposed as a possible treatment in patients with isolated or predominant hypertriglyceridemia in the context of HAART to decrease the higher level of triglycerides.

All Other Miscellaneous Chemical Product and Preparation Manufacturing, Chemical preparations, not elsewhere classified, Unsaturated Fatty Acids, Health aspects, Diagnosis, HIV patients, Highly active antiretroviral therapy, Clinical report

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Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts

Article Abstract:

Children of women who took AIDS drugs during pregnancy probably will not develop mitochondrial disease. Although two such cases have been reported, a review of the medical records of over 20,000 children of HIV-infected women found that none of the 223 who died had died of mitochondrial disease.

Patient outcomes, Mortality, Children, Drug therapy, HIV infections, Mitochondria, Pregnancy, HIV infection in pregnancy

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Absence of association between individual thymidine analogues or nonucleoside analogues and lipid abnormalities in HIV-1-infected persons on initial therapy

Article Abstract:

Researchers have found no effect of several different AIDS drugs on blood cholesterol or triglyceride levels. Older age was linked to high cholesterol levels. Only nucleoside and non-nucleoside drugs were evaluated, not protease inhibitors.

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